Bruno Rivas-Santiago Selected Research

Antimicrobial Cationic Peptides

1/2021	Long-term exposure to particulate matter from air pollution alters airway β-defensin-3 and -4 and cathelicidin host defense peptides production in a murine model.
1/2020	Evidence that changes in antimicrobial peptides during tuberculosis are related to disease severity, clinical presentation, specific therapy and levels of immune-endocrine mediators.
1/2020	Host Defense Peptide RNase 7 Is Down-regulated in the Skin of Diabetic Patients with or without Chronic Ulcers, and its Expression is Altered with Metformin.
1/2019	Antimicrobial Peptides-based Nanostructured Delivery Systems: An Approach for Leishmaniasis Treatment.
1/2018	RNase 7 but not psoriasin nor sPLA2-IIA associates with Mycobacterium tuberculosis during airway epithelial cell infection.
12/2015	LL-37 immunomodulatory activity during Mycobacterium tuberculosis infection in macrophages.

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Bruno Rivas-Santiago Research Topics

Disease

24	Infections 03/2022 - 08/2005
22	Tuberculosis (Tuberculoses) 01/2021 - 08/2005
7	Communicable Diseases (Infectious Diseases) 01/2021 - 01/2006
6	Ulcer 01/2020 - 01/2012
6	Pulmonary Tuberculosis 01/2018 - 11/2010
5	Diabetic Foot 01/2020 - 01/2012
4	Inflammation (Inflammations) 01/2021 - 01/2016
3	Type 2 Diabetes Mellitus (MODY) 01/2020 - 08/2011
3	Wounds and Injuries (Trauma) 09/2018 - 11/2014
3	Diabetes Mellitus 01/2018 - 08/2011
2	Muscle Cramp (Cramp) 01/2021 - 02/2013
2	Latent Tuberculosis 05/2019 - 08/2011
2	Reinfection 01/2017 - 02/2016
2	Latent Infection 05/2012 - 09/2006
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2021
1	Atopic Dermatitis (Atopic Eczema) 11/2020
1	Dermatitis 11/2020
1	Pleural Tuberculosis 01/2020
1	Bowen's Disease (Disease, Bowen) 01/2019
1	Keratosis 01/2019
1	Leishmaniasis 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Chagas Disease (American Trypanosomiasis) 01/2019
1	Hypoxia (Hypoxemia) 01/2018
1	Vascular Diseases (Vascular Disease) 01/2016
1	Hemolysis 01/2014
1	Pneumonia (Pneumonitis) 01/2013

Drug/Important Bio-Agent (IBA)

16	Antimicrobial PeptidesIBA 01/2021 - 01/2006
7	CytokinesIBA 01/2021 - 12/2005
7	Vitamin D FDA LinkGeneric 01/2021 - 09/2014
7	AntigensIBA 05/2019 - 09/2008
7	Peptides (Polypeptides)IBA 08/2016 - 08/2005
6	DefensinsIBA 01/2021 - 09/2006
6	Antimicrobial Cationic PeptidesIBA 01/2021 - 12/2015
6	CathelicidinsIBA 01/2021 - 03/2008
4	Calcitriol (Calcijex)FDA LinkGeneric 01/2021 - 01/2014
4	Pharmaceutical PreparationsIBA 01/2021 - 01/2013
4	beta-DefensinsIBA 01/2017 - 08/2005
3	Adenosine Monophosphate (AMP)IBA 03/2022 - 01/2012
3	VaccinesIBA 05/2019 - 05/2012
3	Biomarkers (Surrogate Marker)IBA 05/2019 - 08/2011
2	Messenger RNA (mRNA)IBA 01/2021 - 08/2005
2	Dehydroepiandrosterone (DHEA)IBA 01/2021 - 01/2020
2	Metformin (Glucophage)FDA LinkGeneric 01/2020 - 01/2020
2	Ribonuclease 7IBA 01/2020 - 01/2018
2	Chemokine CCL5IBA 02/2018 - 12/2005
2	ChemokinesIBA 02/2018 - 12/2005
2	Interleukin-12 (IL 12)IBA 02/2018 - 12/2005
2	innate defense regulating peptide 1018IBA 01/2018 - 01/2013
2	Isoleucine (L-Isoleucine)FDA Link 02/2016 - 01/2015
2	Metalloproteases (Metalloproteinases)IBA 02/2015 - 11/2014
2	Matrix Metalloproteinases (MMPs)IBA 02/2015 - 11/2014
2	Isoniazid (Ftivazide)FDA LinkGeneric 01/2015 - 01/2014
2	Interferon-gamma (Interferon, gamma)IBA 06/2014 - 11/2010
2	Proteins (Proteins, Gene)FDA Link 06/2014 - 11/2010
2	Tuberculin (PPD)IBA 06/2014 - 11/2010
2	DNA VaccinesIBA 03/2014 - 01/2013
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2014 - 05/2013
2	Interleukin-4 (Interleukin 4)IBA 04/2012 - 11/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2008 - 12/2005
1	SmokeIBA 01/2021
1	VitaminsIBA 01/2021
1	Vitamin A (Retinol)FDA LinkGeneric 01/2021
1	Histone Deacetylase InhibitorsIBA 01/2021
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2021
1	Nicotine FDA Link 01/2021
1	Tocopherols (Tocopherol)IBA 01/2021
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021
1	Vitamin E FDA LinkGeneric 01/2021
1	MicronutrientsIBA 01/2021
1	Dinitrochlorobenzene (DNCB)IBA 11/2020
1	caseinomacropeptideIBA 11/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2020
1	Amphotericin B (Amphotericin)FDA LinkGeneric 01/2019
1	S-trichlorovinyl-N-acetylcysteineIBA 01/2019
1	LipidsIBA 01/2019
1	HLA-DR Antigens (HLA-DR)IBA 02/2018
1	Ribonucleases (Ribonuclease)IBA 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	S100 Calcium Binding Protein A7IBA 01/2018
1	Secretory Phospholipases A2IBA 01/2018
1	angiogeninIBA 11/2017
1	Culture MediaIBA 11/2017
1	InterferonsIBA 03/2017
1	Immunologic Factors (Immunomodulators)IBA 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 08/2016
1	human neutrophil peptide 1IBA 04/2016
1	Purinergic P2X7 ReceptorsIBA 12/2015
1	TESIBA 01/2015
1	Calcitriol Receptors (Calcitriol Receptor)IBA 09/2014
1	GoldIBA 06/2014
1	Ethambutol (Myambutol)FDA LinkGeneric 01/2014
1	Rifampin (Rifampicin)FDA LinkGeneric 01/2014
1	IDR 1002IBA 01/2013
1	EnzymesIBA 04/2012
1	ImmunosorbentsIBA 04/2012

Therapy/Procedure

5	Therapeutics 01/2021 - 02/2016
1	Debridement 09/2018
1	Hyperbaric Oxygenation 06/2018